Article
Addressing missing context in regulatory variation across primate evolution.
Current opinion in genetics & development - 1 Aug 2025
Housman Genevieve, Arner Audrey, Longtin Amy, Gagnon Christian, Durvasula Arun, Lea Amanda
Abstract excerpt
In primates, loci associated with adaptive trait variation often fall in noncoding regions. Understanding the mechanisms linking these regulatory variants to fitness-relevant phenotypes remains challenging but can be addressed using functional genomic data. However, such data are rarely generated at scale in nonhuman primates. When they are, only select tissues, cell types, developmental stages, and cellular...
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