Article

Diverse Functions Associate With Non-Coding Trans-species Polymorphisms in Humans

2021-05-28

Abstract excerpt

<h4>Background: </h4> Long-term balancing selection (LTBS) can maintain allelic variation at a locus over millions of years and through speciation events. Variants shared between species, hereafter “trans-species polymorphisms” (TSPs), often result from LTBS due to host-pathogen interactions. For instance, the major histocompatibility complex (MHC) locus contains TSPs present across primates. Several hundred candi...

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Literature Corpus work: 5f17faeb-46b1-5584-a1bb-a0af1d7b54f1
DOI: 10.21203/rs.3.rs-559297/v1

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