Article
Signatures of Long-Term Balancing Selection in Human Genomes.
Genome biology and evolution - 1 Mar 2018
Bitarello Bárbara D, de Filippo Cesare, Teixeira João C, Schmidt Joshua M, Kleinert Philip, Meyer Diogo, Andrés Aida M
Abstract excerpt
Balancing selection maintains advantageous diversity in populations through various mechanisms. Although extensively explored from a theoretical perspective, an empirical understanding of its prevalence and targets lags behind our knowledge of positive selection. Here, we describe the Non-central Deviation (NCD), a simple yet powerful statistic to detect long-term balancing selection (LTBS) that quantifies how...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.