Article

Machine learning reveals the diversity of human 3D chromatin contact patterns

2023-12-23

Abstract excerpt

Understanding variation in chromatin contact patterns across human populations is critical for interpreting non-coding variants and their ultimate effects on gene expression and phenotypes. However, experimental determination of chromatin contacts at a population-scale is prohibitively expensive. To overcome this challenge, we develop and validate a machine learning method to quantify the diversity 3D chromatin co...

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Literature Corpus work: c5f25921-04a7-5442-b16b-40bdf3c42699
DOI: 10.1101/2023.12.22.573104

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