Article

Sequence-to-function deep learning decodes human <i>cis</i> -regulatory evolution

2026-08-27

Abstract excerpt

Deciphering the regulatory consequences of sequence divergence across human evolution is essential to understanding the molecular basis of human-specific traits and disease. Although millions of derived alleles distinguish humans from great apes, only a small fraction are likely to influence human-specific traits. Previous studies have focused on regions of elevated sequence divergence, assuming that rapid evoluti...

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Literature Corpus work: f5af3690-cd58-51a8-9c3c-a7119caec4a5
DOI: 10.64898/2026.08.24.746818

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