Article

B cell receptor analysis using single cell sequencing reveals preferential antibody expression in a HIV candidate vaccine study

2023-04-20

Abstract excerpt

HIV (human immunodeficiency virus) is a virus that infects different cell types in the immune system. While different monoclonal antibodies have been identified, because of the antigenic diversity of HIV, defining broad neutralising antibodies (bnAbs) it has been very challenging. Using the 10x Chromium technology partitioning system, we performed single-cell sequencing of the B cell repertoire and analysed a coho...

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Literature Corpus work: c54d5b09-caa5-57a3-a957-68b8a799d249
DOI: 10.1101/2023.04.18.23288724

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