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Article

Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine

16 Jun 2022

Abstract excerpt

Abstract RNA-based vaccines against SARS-CoV-2 have proven critical to limiting COVID-19 disease severity and spread. Cellular mechanisms driving antigen-specific responses to these vaccines, however, remain uncertain. Here we identify and characterize antigen-specific cells and antibody responses to the RNA vaccine BNT162b2 using multiple single-cell technologies for in depth analysis of longitudinal samples...

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PMID: 35710908
DOI: 10.1038/s41467-022-31142-5

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