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Article

B cell repertoire sequencing of HIV-1 pediatric elite-neutralizers identifies multiple broadly neutralizing antibody clonotypes

2023-07-07

Abstract excerpt

<h4>ABSTRACT</h4> A limited subset of HIV-1 infected adult individuals typically after at least 2-3 years of chronic infection, develop broadly neutralizing antibodies (bnAbs), suggesting that highly conserved neutralizing epitopes on the HIV-1 envelope glycoprotein are difficult for B cell receptors to effectively target, during natural infection. Recent studies have shown the evolution of bnAbs in HIV-1 infecte...

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Literature Corpus work
f1f86292-4876-5a5a-87c9-67b8ed20745b
DOI
10.1101/2023.07.07.548149
Open publication

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B cell repertoire sequencing of HIV-1 pediatric elite-neutralizers identifies multiple broadly neutralizing antibody clonotypesDOI 10.1101/2023.07.07.548149
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