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High-Throughput B Cell Epitope Determination by Next-Generation Sequencing

23 Mar 2022

Abstract excerpt

Development of novel technologies for the discovery of human monoclonal antibodies has proven invaluable in the fight against infectious diseases. Among the diverse antibody repertoires elicited by infection or vaccination, often only rare antibodies targeting specific epitopes of interest are of potential therapeutic value. Current antibody discovery efforts are capable of identifying B cells specific for a...

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Identifiers

PMID: 35401559
DOI: 10.3389/fimmu.2022.855772

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