Article

Shared HIV envelope-specific B cell clonotypes induced by a pox-protein vaccine regimen

2021-08-26

Abstract excerpt

<h4>Summary</h4> An effective HIV-1 vaccine will likely induce potent, broad neutralizing antibodies. No candidate vaccines have elicited these responses presumably because they fail to activate human B cell precursors that can affinity mature to generate broad neutralizing antibodies. To identify the B cell clonotypes that are elicited, we conducted in-depth analyses of the envelope-specific B cell repertoire in...

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Identifiers and source

Literature Corpus work: 0fff8542-81db-508c-bbf9-970665e62990
DOI: 10.1101/2021.08.23.21262508

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