Article

Inferring CTCF binding patterns and anchored loops across human tissues and cell types

2022-06-17

Abstract excerpt

CCCTC-binding factor (CTCF) is a transcription regulator which is involved in many cellular processes. How CTCF recognizes DNA sequence to exert chromosome barrier or enhancer blocking effects remains to be fully interrogated. Despite many computational tools were developed to predict CTCF-mediated loops qualitatively or quantitatively, few could specially evaluate the regulatory potential of DNA sequence at CTCF...

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Literature Corpus work: c4b1cef7-7f35-53cd-8400-5d747dcc9215
DOI: 10.1101/2022.06.15.496356

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