Article

HiC-LDNet: A general and robust deep learning framework for accurate chromatin loop detection in genome-wide contact maps

2022-02-01

Abstract excerpt

<h4>Motivation</h4> Identifying chromatin loops from genome-wide interaction matrices like Hi-C data is notoriously difficult. Such kinds of patterns can span through the genome from a hundred kilobases to thousands of kilobases. Most loop patterns are frequently related to biological functions, such as providing contacts between regulatory regions and promoters. They can also affect the cell-specific biological...

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Literature Corpus work: 10fcb5c5-60bb-56d4-b11e-29f909bd691b
DOI: 10.1101/2022.01.30.478367

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