Article

Predicting unrecognized enhancer-mediated genome topology by an ensemble machine learning model

2020-04-13

Abstract excerpt

Transcriptional enhancers commonly work over long genomic distances to precisely regulate spatiotemporal gene expression patterns. Dissecting the promoters physically contacted by these distal regulatory elements is essential for understanding developmental processes as well as the role of disease-associated risk variants. Modern proximity-ligation assays, like HiChIP and ChIA-PET, facilitate the accurate identifi...

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Literature Corpus work: de4d6f97-0d01-5c71-8a01-a70cc0e18874
DOI: 10.1101/2020.04.10.036145

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