Article

Integrating epigenome and sequence features for CTCF-mediated chromatin loop prediction using LightGBM

2024-12-13

Abstract excerpt

<title>Abstract</title> <p>Background The three-dimensional structure of the human genome is folded to form many loops, which are involved in some critical structural chromatin proteins. The DNA binding protein ccctc-binding factor (CTCF) anchors the chromatin loop. Most anchoring loops of CTCF junctions have the same orientation verifying that CTCF’s directionality is inherited. The features that accurately dis...

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Literature Corpus work: 539b7d25-2c4b-5e4d-b073-d75d64051277
DOI: 10.21203/rs.3.rs-5438447/v1

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