Article

Genomic prediction of coronary heart disease

2016-02-26

Abstract excerpt

<h4>Background</h4> Genetics plays an important role in coronary heart disease (CHD) but the clinical utility of a genomic risk score (GRS) relative to clinical risk scores, such as the Framingham Risk Score (FRS), is unclear. <h4>Methods</h4> We generated a GRS of 49,310 SNPs based on a CARDIoGRAMplusC4D Consortium meta-analysis of CHD, then independently tested this using five prospective population cohorts (t...

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Literature Corpus work: c4b4af9e-cba9-59a2-8f81-0986e919d7dc
DOI: 10.1101/041483

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