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Article

Polygenic risk in early-onset coronary artery disease with low prevalence of traditional cardiovascular risk factors.

Journal of cardiovascular medicine (Hagerstown, Md.) - 1 May 2026

Rossi Maddalena, Conti Andrea, Gagno Giulia, Cappellani Stefania, Altinier Alessandro, Fabris Enrico, Perotto Maria, De Bellis Annamaria, Indennidate Carla, Paldino Alessia, Barbati Giulia, Sinagra Gianfranco, Dal Ferro Matteo, d'Adamo Adamo Pio

Abstract excerpt

AIMS: We aimed to investigate the potential role of polygenic risk in early-onset coronary artery disease (CAD) and recurrence of major adverse coronary events (MACE) in patients with low prevalence of traditional cardiovascular risk factors (CVRFs). METHODS: This was a prospective study enrolling a cohort of patients with early-onset CAD (<50 years) despite no/few traditional CVRFs. Baseline CAD risk was...

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PMID: 42187092
DOI: 10.2459/JCM.0000000000001874

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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