Article

Evaluation of nanopore sequencing for epigenetic epidemiology: a comparison with DNA methylation microarrays

2022-03-04

Abstract excerpt

Most epigenetic epidemiology to date has utilized microarrays to identify positions in the genome where variation in DNA methylation is associated with environmental exposures or disease. However, these profile less than 3% of DNA methylation sites in the human genome, potentially missing affected loci and preventing the discovery of disrupted biological pathways. Third generation sequencing technologies, includin...

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Literature Corpus work: c158e373-9e57-55f8-a2d4-72e74b655a87
DOI: 10.1101/2022.03.01.482537

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