Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-scale DNA methylation analysis.

Epigenomics - 1 Feb 2010

Fouse Shaun D, Nagarajan Raman O, Costello Joseph F

Abstract excerpt

The haploid human genome contains approximately 29 million CpGs that exist in a methylated, hydroxymethylated or unmethylated state, collectively referred to as the DNA methylome. The methylation status of cytosines in CpGs and occasionally in non-CpG cytosines influences protein–DNA interactions, gene expression, and chromatin structure and stability. The degree of DNA methylation at particular loci may be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bayes Theorem
Share to CpG Islands
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Restriction Enzymes

Share to Genome, Human

Share to Immunoprecipitation

Share to Oligonucleotide Array Sequence Analysis

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 20657796
DOI: 10.2217/epi.09.35
PMCID: PMC2907108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-scale DNA methylation analysis.PMID 20657796Read ↗

Genome-wide analysis of DNA methylation patterns.Semantic proximity Read ↗

Genome-wide distribution of DNA methylation at single-nucleotide resolution.Semantic proximity Read ↗

A Summary of the Biological Processes, Disease-Associated Changes, and Clinical Applications of DNA Methylation.Semantic proximity Read ↗

Comparing methylation levels assayed in GC-rich regions with current and emerging methodsSemantic proximity Read ↗

Future impact of integrated high-throughput methylome analyses on human health and disease.Semantic proximity Read ↗

Next generation sequencing in epigenetics: insights and challenges.Semantic proximity Read ↗

Genetic impacts on DNA methylation: research findings and future perspectives.Semantic proximity Read ↗

DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker.Semantic proximity Read ↗

Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome.Semantic proximity Read ↗

"Same Difference": Comprehensive evaluation of three DNA methylation measurement platformsSemantic proximity Read ↗

DNA methylation and DNA methyltransferases.Semantic proximity Read ↗

Mapping of Variable DNA Methylation Across Multiple Cell Types Defines a Dynamic Regulatory Landscape of the Human Genome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.