Article
Future impact of integrated high-throughput methylome analyses on human health and disease.
Journal of genetics and genomics = Yi chuan xue bao - 1 Jul 2008
Butcher Lee M, Beck Stephan
Abstract excerpt
A spate of high-powered genome-wide association studies (GWAS) have recently identified numerous single-nucleotide polymorphisms (SNPs) robustly linked with complex disease. Despite interrogating the majority of common human variation, these SNPs only account for a small proportion of the phenotypic variance, which suggests genetic factors are acting in concert with non-genetic factors. Although environmental...
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