Article

Whole human genome 5’-mC methylation analysis using long read nanopore sequencing

2021-05-21

Abstract excerpt

DNA methylation is a type of epigenetic modification that affects gene expression regulation and is associated with several human diseases. Microarray and short read sequencing technologies are often used to study 5’-methylcytosine (5’-mC) modification of CpG dinucleotides in the human genome. Although both technologies produce trustable results, the evaluation of the methylation status of CpG sites suffers from t...

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Identifiers and source

Literature Corpus work: 8029eaef-2cf5-502f-9b17-daa185178eba
DOI: 10.1101/2021.05.20.444035

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