Article

Simultaneous profiling of chromatin accessibility and methylation on human cell lines with nanopore sequencing

2018-12-22

Abstract excerpt

<h4>ABSTRACT</h4> Understanding how the genome and the epigenome work together to control gene transcription has applications in our understanding of diseases such as human cancer. In this study, we combine the ability of NOMe-seq to simultaneously evaluate CpG methylation and chromatin accessibility, with long-read nanopore sequencing technology, a method we call nanoNOMe. We generated >60Gb whole-genome nanopor...

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Literature Corpus work: 780c90a8-0280-56c7-bfda-2a8466ee42bf
DOI: 10.1101/504993

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