Article

DNA methylation calling tools for Oxford Nanopore sequencing: a survey and human epigenome-wide evaluation

2021-05-06

Abstract excerpt

<h4>Background</h4> Nanopore long-read sequencing technology greatly expands the capacity of long-range single-molecule DNA-modification detection. A growing number of analytical tools have been actively developed to detect DNA methylation from Nanopore sequencing reads. Here, we examine the performance of different methylation calling tools to provide a systematic evaluation to guide practitioners for human epig...

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Literature Corpus work: a44b0309-ee42-5d8b-ae2d-ae137d1b9aef
DOI: 10.1101/2021.05.05.442849

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