Article

An allele-resolved nanopore-guided tour of the human placental methylome

2023-02-13

Abstract excerpt

The placenta is a temporary organ present during pregnancy that is responsible for coordinating all aspects of pregnancy between the mother and fetus. It has a distinct epigenetic, transcriptomic, and mutational landscape with low levels of methylation, high numbers of transcribed loci, and a high mutational burden relative to somatic tissues. We present this landscape through the application of nanopore sequencin...

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Literature Corpus work: 8069ca20-5592-55d7-bc36-6c19e5356c4e
DOI: 10.1101/2023.02.13.528289

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