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A reproducible human brain tissue model to study physiological and disease-associated microglia phenotypes

2026-01-21

Abstract excerpt

Stem-cell-based in vitro models offer promising potential to elucidate human brain cell functions and interactions under physiological and pathological conditions. However, harnessing this potential is impaired by low reproducibility, maturity, or cell-type diversity of existing models. Especially, prolonged incorporation of mature microglia and studies of neuroinflammation have proven challenging. Here, we devel...

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Literature Corpus work
c0df0c93-6549-5ccc-82ea-36b00efb080a
DOI
10.64898/2026.01.20.699077
Open publication

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