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A single cell-based atlas of human microglial states reveals associations with neurological disorders and histopathological features of the aging brain

2018-06-11

Abstract excerpt

Recent studies of bulk microglia have provided insights into the role of this immune cell type in central nervous system development, homeostasis and dysfunction. Nonetheless, our understanding of the diversity of human microglial cell states remains limited; microglia are highly plastic and have multiple different roles, making the extent of phenotypic heterogeneity a central question, especially in light of the...

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Literature Corpus work
e9c103ec-4648-57f9-84e1-0c367dbd2d8f
DOI
10.1101/343780
Open publication

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A single cell-based atlas of human microglial states reveals associations with neurological disorders and histopathological features of the aging brainDOI 10.1101/343780
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