Article

Baseline and Innate Immune Response Characterization of a <i>Zfp30</i> Knockout Mouse Strain

2020-06-18

Abstract excerpt

Airway neutrophilia is correlated with disease severity in a number of chronic and acute pulmonary diseases, and dysregulation of neutrophil chemotaxis can lead to host tissue damage. The gene Zfp30 was previously identified as a candidate regulator of neutrophil recruitment to the lungs and secretion of CXCL1, a potent neutrophil chemokine, in a genome-wide mapping study using the Collaborative Cross. ZFP30 is a...

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Literature Corpus work: bfd99bf5-4294-5309-b5b4-e4023f5f5d49
DOI: 10.1101/2020.06.17.154526

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