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Article

Baseline and innate immune response characterization of a Zfp30 knockout mouse strain.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2020

Laudermilk Lucas T, Tovar Adelaide, Homstad Alison K, Thomas Joseph M, McFadden Kathryn M, Tune Miriya K, Cowley Dale O, Mock Jason R, Ideraabdullah Folami, Kelada Samir N P

Abstract excerpt

Airway neutrophilia is correlated with disease severity in a number of chronic and acute pulmonary diseases, and dysregulation of neutrophil chemotaxis can lead to host tissue damage. The gene Zfp30 was previously identified as a candidate regulator of neutrophil recruitment to the lungs and secretion of CXCL1, a potent neutrophil chemokine, in a genome-wide mapping study using the Collaborative Cross. ZFP30 is a...

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Identifiers

PMID: 32860515
DOI: 10.1007/s00335-020-09847-z
PMCID: PMC7486244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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