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Addressing technical pitfalls in pursuit of molecular factors that mediate immunoglobulin gene regulation

2024-03-08

Abstract excerpt

The expressed antibody repertoire is a critical determinant of immune-related phenotypes. Antibody-encoding transcripts are distinct from other expressed genes because they are transcribed from somatically rearranged gene segments. Human antibodies are composed of two identical heavy and light chain polypeptides derived from genes in the immunoglobulin heavy chain (IGH) locus and one of two light chain loci. The c...

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Literature Corpus work
bcf15f59-5e1f-51bf-a3da-08a62e3cc054
DOI
10.1101/2024.03.06.582860
Open publication

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Addressing technical pitfalls in pursuit of molecular factors that mediate immunoglobulin gene regulationDOI 10.1101/2024.03.06.582860
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