Article

H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion by activating TRNP1 expression

2021-03-06

Abstract excerpt

<h4>ABSTRACT</h4> Increase in the size of human neocortex, acquired in evolution, accounts for the unique cognitive capacity of humans. This expansion appears to reflect the evolutionarily-enhanced proliferative ability of basal progenitors (BPs) in mammalian cortex, which may have been acquired through epigenetic alterations in BPs. However, whether or how the epigenome in BPs differs across species is not known...

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Literature Corpus work: bc5ae730-8f31-58b7-823e-e6546a449524
DOI: 10.1101/2021.03.06.434209

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