Article

Human-specific <i>ARHGAP11B</i> induces hallmarks of neocortical expansion in developing ferret neocortex

2018-08-20

Abstract excerpt

The evolutionary increase in size and complexity of the primate neocortex is thought to underlie the higher cognitive abilities of humans. ARHGAP11B is a human-specific gene that, based on its expression pattern in fetal human neocortex and progenitor effects in embryonic mouse neocortex, has been proposed to have a key function in the evolutionary expansion of the neocortex. Here, we study the effects of ARHGAP...

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Literature Corpus work: 20a267d4-ceff-5b7f-abc2-d5d593e5fb23
DOI: 10.1101/395830

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