Article

Human-specific morphoregulatory signatures in basal radial glia characterize neocortex evolution

2025-03-13

Abstract excerpt

As the seat of our cognition, the human neocortex is an object of immense fascination. Human neocortex expansion during evolution has been attributed to an increase in the proliferative capacity of neural progenitor cells during development, particularly basal radial glia (bRG). Despite their evolutionary relevance, the genomic changes driving human-specific bRG biology remain uncharacterized. We used comparative...

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Literature Corpus work: a672f75c-b214-5a0c-9876-b8acbedb621c
DOI: 10.1101/2025.03.12.642828

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