Article

A human-specific enhancer fine-tunes radial glia potency and corticogenesis

2024-04-11

Abstract excerpt

<h4>Summary</h4> Humans evolved an extraordinarily expanded and complex cerebral cortex, associated with developmental and gene regulatory modifications 1–3 . Human accelerated regions (HARs) are highly conserved genomic sequences with human-specific nucleotide substitutions. Although there are thousands of annotated HARs, their functional contribution to human-specific cortical development is largely unknown 4...

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Literature Corpus work: 2bb719e4-108c-5e1d-b2ad-9c5ebf782584
DOI: 10.1101/2024.04.10.588953

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