Article

Epigenome profiling identifies H3K27me3 regulation of extra-cellular matrix composition in human corticogenesis

2024-10-02

Abstract excerpt

<h4>Summary</h4> Epigenetic mechanisms regulate gene expression programs during neurogenesis, but the extent of epigenetic remodelling during human cortical development remains unknown. Here, we characterize the epigenetic landscape of the human developing neocortex by leveraging Epi-CyTOF, a mass cytometry-based approach for the simultaneous single cell analysis of more than 30 epigenetic marks. We identify H3K2...

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Literature Corpus work: 29b873cf-e267-5092-bfb1-f3dee78905a5
DOI: 10.1101/2024.10.01.616076

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