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Article

Bile acids inhibit Notch-1 expression in the development of Barrett’s esophagus

2019-10-21

Abstract excerpt

<title>Abstract</title> <p>Background: Barrett’s esophagus (BE) is the premalignant condition for the development of esophageal adenocarcinoma, and occurs when the stratified epithelium is replaced by an intestinal-type epithelium with goblet cells. Bile acids (BAs) may play a dominant role in esophageal metaplasia, which is characterized by the expression of intestine-specific nuclear transcription factor caudal...

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Literature Corpus work
bbfe20d7-8ab4-5306-a352-df9650dcf1da
DOI
10.21203/rs.2.16215/v1
Open publication

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