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Article

The Molecular Pathogenesis of Barrett’s Esophagus: Common Signaling Pathways in Embryogenesis Metaplasia and Neoplasia

15 Sept 2009

Abstract excerpt

Although Barrett's esophagus has been recognized for over 50 years, the cellular and molecular mechanisms leading to the replacement of squamous esophageal epithelium with a columnar type are largely unknown. Barrett's is known to be an acquired process secondary to chronic gastroesophageal reflux disease and occurs in the presence of severe disruption of the gastroesophageal barrier and reflux of a mixture of...

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PMID: 19760304
DOI: 10.1007/s11605-009-1011-7

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