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Article

Molecular mechanisms of Barrett's esophagus.

Digestive diseases and sciences - 1 Dec 2011

Chen Hao, Fang Yu, Tevebaugh Whitney, Orlando Roy C, Shaheen Nicholas J, Chen Xiaoxin

Abstract excerpt

Barrett's esophagus (BE) is defined as the metaplastic conversion of esophageal squamous epithelium to intestinalized columnar epithelium. As a premalignant lesion of esophageal adenocarcinoma (EAC), BE develops as a result of chronic gastroesophageal reflux disease (GERD). Many studies have been conducted to understand the molecular mechanisms of this disease. This review summarizes recent results involving...

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Identifiers

PMID: 21984436
DOI: 10.1007/s10620-011-1885-6
PMCID: PMC3750118

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