Article

Bile acids increase intestinal markers via FXR/SNAI2/miR-1 axis in the stomach

2020-05-15

Abstract excerpt

<title>Abstract</title> <p>Background Intestinal metaplasia (IM) is a precancerous lesion that increases risk of subsequent gastric cancer (GC). However, factors governing the transformation from normal gastric epithelial cells to IM remain unclear. Previously, miR-1 turned out to play an essential role in the initiation of bile acids (BA)-induced IM. Here, we investigate the mechanism underlying miR-1 inhibitio...

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Literature Corpus work: 293ad3be-8bae-5aff-83d2-dcd65dd4584e
DOI: 10.21203/rs.3.rs-27417/v1

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