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Article

Barrett esophagus

29 Nov 2012

Abstract excerpt

The incidence of esophageal adenocarcinoma (EAC) is rapidly rising in the western world and accounts for 2% of all cancer-related deaths. The precursor lesion for EAC is Barrett esophagus (BE), which is strongly associated with gastresophageal reflux disease. A major limitation to the study of EAC has been the absence of tractable and genetically modifiable preclinical models of BE. A mouse model of BE and EAC...

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Identifiers

PMID: 23095673
DOI: 10.4161/cc.22485

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