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Article

Cellular mechanisms of Barrett's esophagus development.

Surgical oncology clinics of North America - 1 Jul 2009

Barbera Mariagnese, Fitzgerald Rebecca C

Abstract excerpt

Barrett's esophagus (BE) is a metaplastic premalignant disorder in which the normal stratified squamous epithelium of the lower esophagus is replaced by a columnar lined epithelium with intestinal differentiation. BE generally occurs in the context of chronic gastroesophageal reflux disease and it is the primary risk factor for the development of esophageal adenocarcinoma, with a conversion rate of 0.5% to 1% per...

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Identifiers

PMID: 19500732
DOI: 10.1016/j.soc.2009.03.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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