Article

Widespread RNA editing dysregulation in Autism Spectrum Disorders

2018-10-17

Abstract excerpt

Autism spectrum disorder (ASD) is a genetically complex, clinically heterogeneous neurodevelopmental disease. Recently, our understanding of the molecular abnormalities in ASD has been expanded through transcriptomic analyses of postmortem brains. However, a crucial molecular pathway involved in synaptic development, RNA editing, has not yet been studied on a genome-wide scale. Here, we profiled the global pattern...

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Literature Corpus work: bb4a06cb-434e-5c0d-9eba-5c56dc9ece84
DOI: 10.1101/446625

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