Article
Mammalian conserved ADAR targets comprise only a small fragment of the human editosome.
Genome biology - 7 Jan 2014
Pinto Yishay, Cohen Haim Y, Levanon Erez Y
Abstract excerpt
BACKGROUND: ADAR proteins are among the most extensively studied RNA binding proteins. They bind to their target and deaminate specific adenosines to inosines. ADAR activity is essential, and the editing of a subset of their targets is critical for viability. Recently, a huge number of novel ADAR targets were detected by analyzing next generation sequencing data. Most of these novel editing sites are located in...
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