Alternative splicing in autism spectrum disorder: Recent insights from mechanisms to therapy

Abstract excerpt

Alternative splicing (AS) is a vital and highly dynamic RNA regulatory mechanism that allows a single gene to generate multiple mRNA and protein isoforms. Dysregulation of AS has been identified as a key contributor to the pathogenesis of autism spectrum disorders (ASD). A comprehensive understanding of aberrant splicing mechanisms and their functional consequences in ASD can help uncover the molecular basis of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to RNA regulation and disease
• Share to RNA Research and Splicing
• Share to Viral Infections and Immunology Research