Article

Divergent landscapes of A-to-I editing in postmortem and living human brain

2024-05-09

Abstract excerpt

<h4>ABSTRACT</h4> Adenosine-to-inosine (A-to-I) editing is a prevalent post-transcriptional RNA modification within the brain. Yet, most research has relied on postmortem samples, assuming it is an accurate representation of RNA biology in the living brain. We challenge this assumption by comparing A-to-I editing between postmortem and living prefrontal cortical tissues. Major differences were found, with over 70,...

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Literature Corpus work: b8cb1d06-eca5-5558-ac7c-5491f5b6f543
DOI: 10.1101/2024.05.06.24306763

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