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Article

Evolutionary and ontogenetic changes in RNA editing in human, chimpanzee, and macaque brains.

RNA (New York, N.Y.) - 1 Dec 2013

Li Zhongshan, Bammann Hindrike, Li Mingshuang, Liang Hongyu, Yan Zheng, Phoebe Chen Yi-Ping, Zhao Min, Khaitovich Philipp

Abstract excerpt

Adenosine-to-inosine (A-to-I) substitutions are the most common type of RNA editing in mammals. A-to-I RNA editing is particularly widespread in the brain and is known to play important roles in neuronal functions. In this study we investigated RNA-editing changes during human brain development and maturation, as well as evolutionary conservation of RNA-editing patterns across primates. We used high-throughput...

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Identifiers

PMID: 24152549
DOI: 10.1261/rna.039206.113
PMCID: PMC3884655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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