Article

Exploration of the Roles of HLAs When Predicting Infection Status by T Cell Receptors

2024-11-21

Abstract excerpt

T cells are critical components of human immune system. When a cell is infected by a virus, it presents viral peptides on its surface using human leukocyte antigen (HLA) proteins. These peptide-HLA complexes are recognized by T cells through interactions with T cell receptors (TCRs). A human blood sample can contain millions of unique TCRs, which is a sample from the TCR repertoire of the individual. TCR repertoir...

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Literature Corpus work: bad64a2c-7c4f-5a66-b5cf-876a107e8495
DOI: 10.1101/2024.11.18.624054

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