Article

Immune signatures of common exposures through co-occurrence of T-cell receptors in tens of thousands of donors

2024-03-27

Abstract excerpt

<h4>Background</h4> Memory T cells are records of clonal expansion from prior immune exposures such as infections, vaccines and chronic diseases. Some of the receptors of these expanded T cell clones in a typical immune repertoire are highly public (present in many individuals) because they respond to the same peptide from a prevalent immune exposure, presented by the same Human Leukocyte Antigen (HLA) allele. On...

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Literature Corpus work: 4d532fe9-6133-5ed3-a1d6-f1a2499628eb
DOI: 10.1101/2024.03.26.583354

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