Article

Single-cell analysis of chromatin silencing programs in development and tumor progression

2020-09-04

Abstract excerpt

Single-cell analysis has become a powerful approach for the molecular characterization of complex tissues. Methods for quantifying gene expression 1 and chromatin accessibility 2 of single cells are now well-established, but analysis of chromatin regions with specific histone modifications has been technically challenging. Here, we adapt the recently published CUT&Tag method 3 to scalable single-cell platforms...

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Literature Corpus work: b937cd64-a4f9-52ec-b67d-8ee57dffe495
DOI: 10.1101/2020.09.04.282418

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