Article

Resolving brain organoid heterogeneity by mapping single cell genomic data to a spatial reference

2020-01-07

Abstract excerpt

<h4>ABSTRACT</h4> Self-organizing tissues resembling brain regions grown in vitro from human stem cells (so-called organoids or spheroids) offer exciting possibilities to study human brain development, disease, and evolution. Brain organoids or spheroids are complex and can contain cells at various stages of differentiation from different brain structures. Single-cell genomic methods provide powerful approaches t...

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Literature Corpus work: e8c826dc-13a8-5d21-85f2-deffd6146a5f
DOI: 10.1101/2020.01.06.896282

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