Article

Identification of Potential Novel Pleiotropic Susceptibility Variants Common To Lumbar Spine Bone Mineral Density And Birth Weight

2021-06-30

Abstract excerpt

<title>Abstract</title> <p>An increasing number of epidemiological studies have suggested that birth weight (BW) may be a determinant of bone health later in life, although the underlying genetic mechanism remains unclear. Here, we applied a pleiotropic conditional false discovery rate (cFDR) approach to the genome-wide association study (GWAS) summary statistics for lumbar spine bone mineral density (LS BMD) and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b73a3dd8-2d58-5a86-9a7a-e82e61bd256d
DOI: 10.21203/rs.3.rs-633182/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of Potential Novel Pleiotropic Susceptibility Variants Common To Lumbar Spine Bone Mineral Density And Birth WeightDOI 10.21203/rs.3.rs-633182/v1Read

Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weight.Semantic proximity Read

Identification of Novel Potentially Pleiotropic Variants Associated With Osteoporosis and Obesity Using the cFDR Method.Semantic proximity Read

Pleiotropic genomic variants at 17q21.31 associated with bone mineral density and body fat mass: a bivariate genome-wide association analysis.Semantic proximity Read

Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci.Semantic proximity Read

Enhanced Identification of Potential Pleiotropic Genetic Variants for Bone Mineral Density and Breast Cancer.Semantic proximity Read

Identification of novel pleiotropic gene for bone mineral density and lean mass using the cFDR method.Semantic proximity Read

A Genomewide Association Study Identifies Two Sex‐Specific Loci, at SPTB and IZUMO3, Influencing Pediatric Bone Mineral Density at Multiple Skeletal SitesSemantic proximity Read

Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density.Semantic proximity Read

Two novel pleiotropic loci associated with osteoporosis and abdominal obesity.Semantic proximity Read

Transcriptome-wide association study identifies novel genes associated with child body mineral density and lean body massSemantic proximity Read

Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk.Semantic proximity Read

Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density.Semantic proximity Read