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A Genomewide Association Study Identifies Two Sex‐Specific Loci, at SPTB and IZUMO3, Influencing Pediatric Bone Mineral Density at Multiple Skeletal Sites

9 Feb 2017

Abstract excerpt

ABSTRACT Failure to achieve optimal bone mineral accretion during childhood and adolescence results in subsequent suboptimal peak bone mass, contributing to osteoporosis risk later in life. To identify novel genetic factors that influence pediatric bone mass at discrete skeletal sites, we performed a sex‐stratified genomewide association study of areal bone mineral density (BMD) measured by dual‐energy X‐ray...

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PMID: 28181694
DOI: 10.1002/jbmr.3097

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